Dermatologie, Venerologie und Allergologie -
Prof. Dr. Roland Kaufmann

 

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Expertise

  • Rolle von Hautzellen bei chronisch-entzündlichen Erkrankungen (T-Zellen, Endothelzellen und Keratinozyten bei Psoriasis, atopischer Dermatitits etc. – Prof. W.-H. Boehncke)
  • Funktionelle Untersuchungen zur Perzeption und Signaltransduktion von mechanischen Reizen (Druck, Zug – PD Dr. S. Kippenberger)
    Transplantation autologer Keratinozyten und Fibroblasten bei Brandopfern (Prof. A. Bernd)
  • Möglichkeiten neuer Lasertechnologien in der dermatologischen Therapie (Prof. R. Kaufmann)
  • Immunochemotherapie des Melanoms (Prof. R. Kaufmann)
  • Regulation von Angiogenesefaktoren in der Haut (Prof. J. Gille)
  • Antigen-Prozessierung und –Präsentation (Prof. W.-H. Boehncke)
  • Bedeutung von oxidativem Streß bei männlicher Infertilität (Prof. F. Ochsendorf)

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Methoden und Geräte

  • Zellkulturmodelle zur Testung von Pharmaka und Kosmetika
    (Prof. A. Bernd in Kooperation mit der Firma Phenion GmbH&CoKG)
  • Xenograft Tumor-Modelle an Nacktmäusen (Dr. M. Hofmann)

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Mitarbeiter

  • Prof. Dr. R. Kaufmann
  • Prof. Dr. W.-H. Boehncke
  • Prof. Dr. A. Bernd
  • Prof. Dr. F.Ochsendorf
  • Prof. Dr. J. Gille
  • OA Dr. D. Thaci
  • PD Dr. S. Kippenberger
 

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Publikationen

  • Meissner M, Kaufmann R. [Pseudoxanthoma elasticum with "angioid streaks" (Grönblad-Strandberg syndrome)] Dtsch Med Wochenschr (2008) 133: 959-960.
  • Schmidt H, Ochsendorf FR, Wolter M, Geisslinger G, Ludwig RJ, Kaufmann R. Topical 5-fluorouracil in Darier disease. Br J Dermatol (2008) Apr 10: Epub ahead of print.
  • Kaufmann R, Spelman L, Weightman W, Reifenberger J, Szeimies RM, Verhaeghe E, Kerrouche N, Sorba V, Villemagne H, Rhodes LE. Multicentre intraindividual randomized trial of topical methyl aminolaevulinate-photodynamic therapy vs. cryotherapy for multiple actinic keratoses on the extremities. Br J Dermatol (2008) 158: 994-999.
  • Meissner M, Pinter A, Michailidou D, Hrgovic I, Kaprolat N, Stein M, Holtmeier W, Kaufmann R, Gille J. Microtubule-Targeted Drugs Inhibit VEGF Receptor-2 Expression by both Transcriptional and Post-Transcriptional Mechanisms. J Invest Dermatol (2008) Mar 6: Epub ahead of print.
  • Meissner M, Whiteside TL, van Kuik-Romein P, Valesky EM, van den Elsen PJ, Kaufmann R, Seliger B. Loss of interferon-gamma inducibility of the MHC class II antigen processing pathway in head and neck cancer: evidence for post-transcriptional as well as epigenetic regulation. Br J Dermatol. (2008) 158: 930-940.
  • Zöller NN, Kippenberger S, Thaçi D, Mewes K, Spiegel M, Sättler A, Schultz M, Bereiter-Hahn J, Kaufmann R, Bernd A. Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model. Toxicol In Vitro (2008) 22: 747-759.
  • Spieth K, Kaufmann R, Dummer R, Garbe C, Becker JC, Hauschild A, Tilgen W, Ugurel S, Beyeler M, Bröcker EB, Kaehler KC, Pföhler C, Gille J, Leiter U, Schadendorf D. Temozolomide plus pegylated interferon alfa-2b as first-line treatment for stage IV melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group (DeCOG). Ann Oncol. (2008) 19: 801-806.
  • Dorn A, Kippenberger S. Clinical application of CpG-, non-CpG-, and antisense oligodeoxynucleotides as immunomodulators. Curr Opin Mol Ther (2008) 10: 10-20.
  • Rubant S, Ludwig RJ, Diehl S, Hardt K, Kaufmann R, Pfeilschifter JM, Boehncke WH. Dimethylfumarate reduces leukocyte rolling in vivo through modulation of adhesion molecule expression. J Invest Dermatol (2008) 128: 326-331.
  • Schindewolf M*, Ludwig RJ*, Wolter M, Himsel A, Zgouras D. Kaufmann R, Boehncke WH, Lindhoff-Last E (*equal contributors). Tolerance of fondaparinux in patients with generalized contact dermatitis to heparin. JEAD (2008) 22: 378-380.
  • Böddinghaus BK, Ludwig RJ, Kaufmann R, Enzensberger R, Gies V, Kramme S, Brade V, Brandt CM. Leprosy in a pregnant woman. Infection (2007) 35: 37-39.
  • Boehncke S, Thaci D, Beschmann H, Ludwig RJ, Ackermann H, Badenhoop K, Boehncke WH. Psoriasis shifts the meabolic state towards insulin resistence. Br J Dermatol (2007) 157: 1249-1251.
  • Dorn A, Ludwig RJ, Bock A, Thaçi D, Hardt K, Bereiter-Hahn J, Kaufmann R, Bernd A, Kippenberger S. Oligonucleotides Suppress IL-8 in Skin Keratinocytes In Vitro and Offer Anti-Inflammatory Properties In Vivo. J Invest Derm (2007) 127: 846-854.
  • Dujic J, Kippenberger S, Hoffmann S, Ramirez-Bosca A, Miquel J, Diaz-Alperi J, Bereiter-Hahn J, Kaufmann R, Bernd A: Low concentrations of Curcumin Induce Growth Arrest and Apoptosis in Skin Keratinocytes only in combination with UVA or Visible Light. J Invest Dermatol (2007) 127: 1992-2000.
  • Hofmann M, Schultz M, Bernd A, Bereiter-Hahn J, Kaufmann R, Kippenberger S: Long-term lowering of tumour interstitial fluid pressure reduces Ki-67 expression. J Biomech (2007) 40: 2324-2329.
  • Ludwig RJ, Boehncke WH: Psoriasis and risk of myocardial infarction. JAMA (2007) 297: 362-363.
  • Ludwig RJ, Henke U, Wolter M, Walker SL, Brandt C, Wichelhaus TA, Kramme S, Lockwood DNJ, Kaufmann R: Persistence of peri-neural granulomas after successful treatment of leprosy. J Eur Acad Dermatol (2007) 21: 1414-1416.
  • Ludwig RJ, Herzog C, Rostock A, Ochsendorf FR, Zollner TM, Thaçi; D, Kaufmann R, Vogl TJ, Boehncke WH. Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol (2007) 156: 271-276.
  • Ludwig RJ, Kaufmann R: Herpes zoster sparing area of skin transplant. Lancet (2007) 370:1240.
  • Ludwig RJ*, Schön MP*, Boehncke WH (*equal contributors). P-Selectin - a common therapeutic target for cardiovascular disorders, inflammation, and tumor metastasis? Exp Opin Therap Targets (2007) 11: 1-15.
  • Meissner M, Beier C, Gille J, Kaufmann R. Annular leukocytoclastic vasculitis in association with chronic hepatitis B. J Eur Acad Dermatol Venerol (2007) 21: 135-136.
  • Meissner M, Kaufmann R, Gille J. Sodium Thiosulphate: a new way of treatment for calciphylaxis? Dermatology (2007) 214: 278-282.
  • Meissner M, Spieth K, Wolter M, Boehncke Wh, Thaci D, Kaufmann R: Cutaneous botryomycosis: a rarely diagnsoed bacterial infection of the skin. Hautarzt (2007) 58: 966-968.
  • Oostingh GJ*, Ludwig RJ*, Enders S*, Grüner S, Harms G, Boehncke WH, Nieswandt B, Tauber R, Schön MP (*equal contributors): Diminished lymphocyte adhesion and alleviation of allergic responses by small molecule or antibody-mediated inhibition of L-selectin functions. J Invest Dermatol (2007) 127: 90-97.
  • Oostingh GJ, Pozgajova M, Ludwig RJ, Krahn T, Boehncke WH, Nieswandt B, Schön MP. Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions. Haematologica / The Hematology Journal (2007) 92: 502-512.
  • Schmidtko A, Burian M, Altis K, Hardt K, Angioni C, Schmidt R, Podda M, Geisslinger G. Pharmacological and histopathological characterization of a hyperalgesia model induced by freeze lesion. Pain (2007) 127: 287-295.
  • Boehncke WH, Boehncke S. Toleranz von Etoricoxib bei anamnestischer Intoleranz gegenüber nichtsteroidalen Antirheumartika: eine doppelblinde plazebokontrollierte Studie mit Etoricoxib und Literaturübersicht. Allergo J (2006) 15: 566-571.
  • Boehncke WH, Brasie RA, Barker J, Chimenti S, Daudén E, de Rie M, Dubertret L, Giannetti A, Katsambas A, Kragballe K, Naeyaert JM, Ortonne JP, Peyrí J, Prinz JC, Saurat JH, Strohal R, van de Kerkhof P, Sterry W. European Dermatology Expert Group (2006) Recommendations for the use of etanercept in psoriasis: a European dermatology expert group consensus. J Eur Acad Dermatol (2006) 20: 988-998.
  • Boehncke WH, Prinz J, Gottlieb AB: Biologic therapies for psoriasis. A systematic review. J Rheumatol. (2006) 33: 1447-1451.
  • Bucksch-Beudt C, Büchel A, Berkhoff S, Janko S, Kirchhoff A, Kompatscher J, Kraft HG, Kujumdshiev S, Nürnberger F, Ochsendorf F, Rehner M, Schulze J: Möglichkeiten und Grenzen der Fragebogen-gestützten Erhebung von Soft skills als Zulassungskriterien zum Medizinstudium. Z Med Ausb (2006) 23: Doc65.
  • Cáceres O, Kirschner R, Piepenbring M, Schöfer H, Gené J: Hormographiella verticillata and an Ozonium stage as anamorphs of Coprinellus domesticus. Anton Leeuvw Int J G (2006) 89: 79-90.
  • Dréno B, Bettoli V, Ochsendorf F, Perez-Lopez M, Mobacken H, Degreef H, Layton A: An expert view on the treatment of acne with systemic antibiotics and/or oral isotretinoin in the light of the new European recommendations. Eur J Dermatol (2006) 16: 565-571.
  • Fritzsche J, Alban S, Ludwig RJ, Rubant S, Boehncke WH, Schumacher G, Bendas G: The influence of various structural parameters of semisynthetic sulfated polysaccharides on the P-selectin inhibitory capacity. Biochem Pharmacol. (2006) 72: 474-485.
  • Göttig S, Möbest D, Rüster B, Grace B, Winter S, Seifried E, Gille J, Wieland T, Henschler R: Role of the monomeric GTPase Rho in hematopoietic progenitor cell migration and transplantation. Eur J Immunol (2006) 36: 180-189.
  • Garbe C, Hauschild A, Volkenandt M, Schadendorf D, Stolz W, Kortmann RD, Kettelhack C, Frerich B, Keilholz U, Dummer R, Sebastian G, Tilgen W, Schuler G, Mackensen A, Kaufmann R. Brief guidelines: malignant melanoma of the skin. J Dtsch Dermatol Ges (2006) 4: 344-349.
  • Gille J: Antiangiogenic cancer therapies get their act together: current developments and future prospects of growth factor- and growth factor receptor-targeted approaches. Exp Dermatol (2006) 15: 175-186.
  • Hamm H, Beiteke U, Höger PH, Seitz CS, Thaçi D, Sunderkötter C. Treatment of scabies with 5% permethrin cream: results of a German multicenter study. J Dtsch Dermatol Ges (2006) 4: 407-413 .
  • Hofmann M, Guschel M, Bernd A, Bereiter-Hahn J, Kaufmann R, Tandi C, Wiig H, Kippenberger S. Lowering of tumor interstitial fluid pressure reduce tumor cell proliferation in a xenograft tumor model. Neoplasia (2006) 8: 89-95.
  • Kaufmann R. Malignant melanoma - sentinel lymph node biopsy and surgical procedures. Front Radiat Ther Oncol (2006) 39: 127-139.
  • Kaufmann R, Bieber T, Helgesen AL, Andersen BL, Luger T, Poulin Y, Al-Hafidh J, Paul C (multicentre investigator group). Onset of pruritus relief with pimecrolimus cream 1% in adult patients with atopic dermatitis: a randomized trial. Allergy (2006) 61: 375-381.
  • Kippenberger S, Loitsch S, Thaçi D, Müller J, Guschel M, Kaufmann R, Bernd A: Restoration of E-cadherin sensitizes human melanoma cells for apoptosis. Melanoma Res (2006) 16: 393-403 .
  • Knies Y, Bernd A, Kaufmann R, Bereiter-Hahn J, Kippenberger S. Mechanical Stretch-Induces Clustering of β1-Integrins and Facilitates Adhesion. Experimental Dermatology (2006); 15: 347-355.
  • Lammerding-Köppel M, Fabry G, Hofer M, Ochsendorf F, Schirlo C. Hochschuldidaktische Qualifzierung in der Medizin: II. Anforderungsprofil der Qualifizierungsangebote. Z Med Ausb (2006) 23: Doc72.
  • Lammerding-Köppel M, Fabry G, Hofer M, Ochsendorf F, Schirlo C. Hochschuldidaktische Qualifizierung in der Medizin: I. Bestandsaufnahme. Z Med Ausb (2006) 23: Doc73 .
  • Ludwig RJ, Alban S, Bistrian R, Boehncke WH, Henschler R, Kaufmann R, Gille J. The ability of different forms of heparins to suppress P-selectin function in vitro correlates to their inhibitory capacity on blood-borne metastasis in vivo. Thromb Haemost (2006) 95: 535-540.
  • Ludwig RJ, Alban S, Boehncke WH: Structural requirements of modified glycosaminoglycans to exert polyvalent anti-inflammatory activities. Mini-Rev Med Chem (2006) 6: 1009-1023.
  • Ludwig RJ, Schindewolf M, Utikal J, Lindhoff-Last E, Boehncke WH. Management of cutanenous heparin hypersensitivity reactions. Thromb Haemost (2006) 96: 611-617.
  • Ludwig RJ, Werner RJ, Winker W, Boehncke WH, Wolter M, Kaufmann R. Chronic venous insufficiency – a potential trigger for localized scleroderma. J Eur Acad Dermatol Venerol (2006) 20: 9699.
  • Meissner M, Bauer R, Beier C, Betz C, Wolter M, Kaufmann R, Gille J. Sodium thiosulphate as a promising therapeutic option to treat calciphylaxis. Dermatology (2006) 212: 373-376.
  • Meissner M, Gille J, Kaufmann R: Calciphylaxis. no therapeutic concepts for a poorly understood syndrome? J Dtsch Dermatol Ges (2006) 4: 1037-1044.
  • Meissner M, Varwig D, Beier C, Jacobi V, Kaufmann R, Gille J. Dystrophic calcinosis cutis after subcutaneous administration of para-aminosalicylic acid for treatment of pulmonary tuberculosis. J Dtsch Dermatol Ges (2006) 4: 489-491.
  • Mewes KR, Raus M, Bernd A, Zöller NN, Sattler A, Graf R: Elastin Expression in a Newly Developed Full-Thickness Skin Equivalent. Skin Pharmacol Phys (2006) 20: 85-95.
  • Mrowietz U, Barth J, Boehncke WH, Reich K, Rosenbach T, Streit V, Wozel G. Therapy of psoriasis-arthritis and psoriasis vulgaris with infliximab. J Dtsch Dermatol Ges (2006) 4: 444-447.
  • Mrowietz U, Barth J, Boehncke WH, Reich K, Rosenbach T, Streit V, Wozel G. Therapy of psoriasis vulgaris with efalizumab. J Dtsch Dermatol Ges (2006) 4: 511-512.
  • Mrowietz U, Boehncke WH : Leukocyte adhesion: a suitable target for anti-inflammatory drugs. Curr Pharm Design (2006) 12: 2825-2831.
  • Nash P, Thaçi D, Behrens F, Falk F, Kaltwasser JP. Leflunomide improves psoriasis in patients with psoriatic arthritis: an in-depth analysis of data from the TOPAS study. Dermatology (2006) 212: 238-234.
  • Ochsendorf F. Systemic antibiotic therapy of acne vulgaris. J Dtsch Dermatol Ges (2006) 4: 828-841.
  • Ochsendorf FR. Azoospermia: rational differential diagnosis and conservative therapy. Andrologie (2006) 97: 107-108 .
  • Ochsendorf FR. Clinical relevance of antibiotic resistance in acne. G Ital Dermatol Venereol (2006) 141: 183-186 .
  • Papoutsis NG, Abdel-Naser MB, Altenburg A, Orawa H, Kötter I, Krause L, Pleyer U, Djawari D, Stadler R, Wollina U, Kohl PK, Gollnick HP, Kirch W, Ochsendorf FR, Keitel W, Martus P, Zouboulis CC. Prevalence of Adamantiades-Behçet's disease in Geremany and the municipality of Berlin: Results of a nationwide survey. Clin Exp Rheumatol (2006) 24: S125.
  • Pello OM, Duthey B, Garcìa-Bernal D, Rodrìguez-Frade JM, Stein JV, Teixido J, Martìnez C, Mellado M. Opioids trigger alpha 5 beta 1 integrin-mediated monocyte adhesion. J Immunol (2006) 176: 1675-85 .
  • Pfeffer J, Kaufmann R, Boehncke WH : Das Psoriasis SCID Maus Modell. Hautarzt (2006) 57: 603-609.
  • Rubant S, Ludwig RJ, Pfeffer J, Schulze-Johann P, Kaufmann R, Pfeilschifter JM, Boehncke WH, Radeke HH: Eukaryotic expression of the broad-spectrum chemokine receptor antagonist vMIP-II and its effects on T-cell function in vitro and in vivo. Exp Dermatol (2006) 15: 634-642 .
  • Rüster B, Göttig S, Ludwig RJ, Bistrian R, Müller S, Seifried E, Gille J, Henschler R: Mesenchymal stem cells (MSCs) display coordinated rolling and adhesion behavior on endothelial cells. Blood (2006) 108: 3938-3944.
  • Schöfer H, Brockmeyer NH. Brief guidelines--Kaposi sarcoma. J Dtsch Dermatol Ges (2006) 4: 586-590.
  • Schöfer H, Brockmeyer NH, Hagedorn HJ, Hamouda O, Handrick W, Krause W, Marcus U, Münstermann D, Petry KU, Prange H, Potthoff A, Gross G: Syphilis. Guideline of the German Sexually Transmitted Diseases Society fo diagnosis and therapy of syphilis. J Dtsch Dermatol Ges (2006) 4: 160-177.
  • Schulz C, Kaufmann R, Ochsendorf FR. Generalisierte Purpura als dermatologische Manifestation einer Thrombcytopenie. Hautarzt (2006) 57: 697-700.
  • Schwaner S, Wolter M, Kaufmann R, Boehncke WH. Papules on the right lower leg of an African girl. J Dtsch Dermatol Ges (2006) 4: 681-682.
  • Sommerlad M, Beier C, Kaufmann R. Dermatitis artefacta presenting as photodermatosis. Hautarzt (2006); online-published 17.5.06.
  • Spieth K, Kovàcs A, Wolter M, Bug R, Kaufmann R, Gille J. Topical imiquimod: effectiveness in intraepithelial melanoma of oral mucosa. Lancet Oncol (2006) 7: 1036-1037.
  • Ugurel S, Schadendorf D, Pföhler C, Neuber K, Thoelke A, Ulrich J, Hauschild A, Spieth K, Kaatz M, Rittgen W, Delorme S, Tilgen W, Reinhold U, Dermatologic Cooperative Oncology Group. In vitro drug sensitivity predicts response and survival after individualized sensitivity-directed chemotherapy in metastatic melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group. Clin Cancer Res (2006) 12: 5454-5463.
  • Weller K, Vetter-Kauzcok C, Kähler K, Hauschild A, Eigentler Th, Pföhler C, Neuber K, Moll I, Krause M, Kneisel L, Nashan D, Thoelke A Letsch B., Näher H., Becker J.. Umsetzung von Leitlinien bei seltenen Erkrankungen am Beispiel des Merkelzellkarzinoms. Dt. Ärzteblatt (2006) 103: 2791-2796.
  • White S, Vender R, Thaçi D, Haverkamp C, Naeyaert JM, Foster R, Martinez Escribano JA, Cambazard F, Bibby A. Use of calcipotriene cream (Dovonex cream) following acute treatment of psoriasis vulgaris with the calcipotriene/betamethasone dipropionate two-compound product (Taclonex): a randomized, parallel-group clinical trial. Am J Clin Dermatol (2006) 7: 177-184.
  • Wienrich BG, Krahn T, Schon M, Rodriguez ML, Kramer B, Busemann M, Boehncke WH, Schon MP. Structure-function relation of efomycines, a family of small-molecule inhibitors of selectin functions. J Invest Dermatol (2006) 126: 882-889.
  • Wittekindt BE, Kitz R, Schöfer H, Hoerauf A, Zielen S. Dermatitis and eosinophilia in a 9-year-old girl from Congo: putative onchodermatitis. Klin Padiatr (2006) 218: 41-44.
  • Boehncke S, Boehncke WH. Tolerance to coxib in patients with intolerance to non.steroidal anti-inflammtoy drugs (NSAIDs). Dtsch Med Wochenschr (2005) 130: 2249- 2252.
  • Boehncke WH. The psoriasis SCID mouse model: a tool for drug discovery? Ernst Schering Res Found Workshop (2005) 50: 213-234.
  • Boehncke WH, Ochsendorf FR, Noll S, Urban M, Popp A, Waldherr D, Haunschild J, Litzenburger T.: Efficacy of the fully human monoclonal antibody MOR102 (#5) against intercellular adhesion molecule 1 in the psoriasis-severe combined immunodeficient mouse model. Br J Dermatol. (2005) 153: 758-766..
  • Boehncke WH, Schon MP, Giromolomi G, Bos JD, Thestrup-Pedersen K, Cavani A, Nestle F, Bonish BK, Campbell JJ, Nickoloff B. Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? Exp Dermatol (2005) 14: 70-80.
  • Brill TJ, Elshorst-Schmidt T, Valesky EM, Kaufmann R, Thaçi D. Successful treatment of acrodermatitis continua of hallopeau with sequential combination of calcipotriol and tacrolimus ointments. Dermatology (2005) 211: 351-355.
  • Brill TJ, Ludwig RJ, Wolter M, Oeschger S, Thaçi D, Boehncke WH, Kaufmann R. Complicated mycosis fungoides mimicking facial erysipelas. Br J Dermatol. (2005) 152:1381-1383.
  • Fritzsche J, Hunerbein I, Schumacher G, Alban S, Ludwig R, Gille J, Bendas G. In vitro investigation on the selectin binding mechanisms in tumor cell metastasis and their inhibition by heparin. Int J Clin Pharmacol Ther. (2005) 43: 570-572.
  • Gille J, Spieth K, Kaufmann R. Metronomic low-dose chemotherapy as antiangiogenic therapeutic strategy for cancer. J Dtsch Dermatol Ges. (2005) 3: 26-32.
  • Haas U, Podda M, Behne M, Gurrieri S, Alonso A, Furstenberger G, Pfeilschifter J, Lambeau G, Gelb MH, Kaszkin M. Characterization and differentiation-dependent regulation of secreted phospholipases A in human keratinocytes and in healthy and psoriatic human skin. J Invest Dermatol. (2005) 124: 204-211.
  • Hirsch K*, Ludwig RJ*, Wolter M, Zollner TM, Hardt K, Kaufmann R, Boehncke WH (*equal contributors). Eosinophilic cellulitis (Wells' syndrome) associated with colon carcinoma. J Dtsch Dermatol Ges (2005) 3: 530-531.
  • Kaufmann R, Spieth K, Leiter U, Mauch C, von den Driesch P, Vogt T, Linse R, Tilgen W, Schadendorf D, Becker JC, Sebastian G, Krengel S, Kretschmer L, Garbe C, Dummer R. Dermatologic Cooperative Oncology Group: Temozolomide in combination with interferon-alfa versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, phase III, multicenter study from the Dermatologic Cooperative Oncology Group. J Clin Oncol. (2005) 23: 9001-9007.
  • Kippenberger S, Loitsch S, Guschel M, Müller J, Kaufmann R, Bernd A. Hypotonic stress induces E-cadherin expression in cultured human keratinocytes. FEBS Lett (2005) 579: 207-214.
  • Kippenberger S, Loitsch S, Guschel M, Müller J, Knies Y, Kaufmann R, Bernd A. Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor. J Biol Chem (2005) 280: 3060-3067.
  • Kippenberger S, Loitsch S, Thaçi D, Kaufmann R, Bernd A. Detection of human beta defensin-1 and -2 by RT-competitive multiplex PCR. Arch Dermatol Res. (2005) 296: 539-542.
  • Klauke S, Schoefer H, Althoff PH, Michels B, Helm EB: Sex hormones as a cofactor in the pathogenesis of epidemic Kaposi's sarcoma. AIDS. (1995) 9:1295-1296.
  • Krämer H.-J, Podobinska M, Bartsch A, Battmann A, Thoma W, Bernd A, Kummer W, Irlinger B, Steglich W, Mayser P. Malassezin, a novel agonist of the aryl hydrocarbon receptor from the yeast Malassezia furfur, induces apoptosis in primary human melanocytes. ChemBioChem (2005) 6: 860-865.
  • Ludwig RJ*, Schindewolf M*, Alban S, Kaufmann R, Lindhoff-Last E, Boehncke WH (*equal contributors): Molecular weight determines the frequency of delayed type hyper-sensitivity reactions to heparin and synthetic oligosaccharides. Thromb Haemost (2005) 94: 1265-1269.
  • Ludwig RJ*, Zollner TM*, Santoso S, Hardt K, Gille J, Baatz H, Schulze Johann P, Pfeffer J, Radeke HH, Schön M, Kaufmann R, Boehncke WH, Podda M (*equal contributors). Junctional Adhesion Molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. J Invest Derm (2005) 125: 969-976.
  • Meissner M, Reichert TE, Kunkel M, Gooding W, Whiteside TL, Ferrone S, Seliger B. Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: association with clinical outcome. Clin Cancer Res (2005) 11: 2552-2560.
  • Meissner M, Spieth K, Loffler T, Wolter M, Neudert H, Kaufmann R, Gille J. Red lobular tumor on the dorsal surface of the tongue. J Dtsch Dermatol Ges (2005) 3: 1007-1008.
  • Mrowietz U, Barth J, Boehncke WH, Rosenbach T, Wozel G. Therapy of psoriasis vulgaris and psoriatic arthritis with etanercept. J Dtsch Dermatol Ges (2005) 3: 470-472.
  • Pfeffer J, Kaufmann R, Boehncke WH. Psoriasis SCID-mouse model. Hautarzt (2005) 19.
  • Radeke HH; Ludwig RJ, Boehncke WH. Experimental approaches to lymphocyte migration in dermatology in vitro and in vivo. Exp Dermatol (2005) 14: 641-666.
  • Schöfer H, Brockmeyer N, Dissemond J, Effendy I, Esser S et al.. Staphylokokken-Infektionen der Haut und Schleimhäute. Chemother J (2005) 14: 67-73.
  • Schön M, Ludwig RJ. Lymphocyte trafficking to inflamed skin molecular mechanisms and implications for therapeutic target molecules. Exp Oppin Therap Targets (2005) 9: 225-243.
  • Schon MP, Boehncke WH. Psoriasis. N Engl J Med (2005) 352:1899-1912.
  • Thaçi D, Pätzold S, Kaufmann R, Boehncke WH. Treatment of psoriasis with alefacept in patients with hepatitis C infection: a report of two cases. Br J Dermatol (2005) 152: 1048-1050.
  • Thaçi D, Schöfer H. [Topical antibiotics in skin infections] Hautarzt. (2005) 56: 381-394.
 
   

 

 

INSTITUTE UND MEDIZINISCHE ZENTREN

 
Chemie

Institut für Organische Chemie und Chemische Biologie

Prof. Dr. Joachim W. Engels

Prof. Dr. Michael Göbel

Prof. Dr. Gisbert Schneider

Pharmazie

Institut für Pharmazeutische Biologie

Prof. Dr. Theo Dingermann

Prof. Dr. Rolf Marschalek

Institut für Pharmazeutische Chemie

Prof. Dr. Michael Karas

Prof. Dr. Manfred Schubert-Zsilavecz

Prof. Dr. Holger Stark

Prof. Dr. Dieter Steinhilber

Institut für Pharmazeutische Technologie

Prof. Dr. Jennifer Dressman

Prof. Dr. Jörg Kreuter

Pharmakologisches Institut für Naturwissenschaftler

Prof. Dr. Jochen Klein

Prof. Dr. Walter E. Müller

Gustav-Embden-Zentrum für Biologische Chemie

Institut für
Biochemie I: Pathobiochemie

Prof. Dr. Bernhard Brüne

Zentrum der Hygiene

Medizinische Virologie

Prof. Dr. Hans Wilhelm Doerr

Dr. Senckenbergische Anatomie

Anatomie I: Klinische Neuroanatomie

Prof. Dr. Thomas Deller

Anatomie II: Experimentelle Neurobiologie

Prof. Dr. Horst-Werner Korf

Zentrum der Pharmakologie

Allgemeine Pharmakologie und Toxikologie

Prof. Dr. Josef Pfeilschifter

Immunpharmakologie

Prof. Dr. Heinfried Radeke

Klinische Pharmakologie

Prof. Dr. Dr. Gerd Geißlinger

Zentrum der Physiologie

Physiologie I: Kardiovaskuläre Physiologie

Prof. Dr. Ralf Brandes

Institute for Vascular Signalling

Prof. Dr. Ingrid Fleming

Zentrum für Gesundheits-
wissenschaften

Allgemeinmedizin

Prof. Dr. Ferdinand Gerlach

Zentrum der Anästhesiologie und Wiederbelebung

Anästhesiologie, Intensivmedizin und Schmerztherapie

Prof. Dr. Oliver Habler

Prof. Dr. Paul Kessler

Zentrum der Chirurgie

Klinik für Allgemeinchirurgie

Prof. Dr. Wolf O. Bechstein

Dr. Christiane Gog

Dr. Christoph W. Strey

PD Dr. Christoph Wullstein

Mund-, Kiefer- und Plastische Gesichtschirurgie

Prof. Dr. Dr. Dr. Robert Sader

Zentrum der Dermatologie und Venerologie

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Klinik für Dermatologie, Venerologie und Allergologie

Prof. Dr. Roland Kaufmann

Zentrum der Frauenheilkunde und Geburtshilfe

Klinik für Frauenheilkunde und Geburtshilfe

Prof. Dr. Manfred Kaufmann

Zentrum der Inneren Medizin

Med. Klinik I: Gastroenterologie und Hepatologie, Pneumologie und Allergologie, Endokrinologie und Diabetologie sowie Ernährungsmedizin

Prof. Dr. Christoph Sarrazin

PD Dr. Dr. Oliver Schröder

Prof. Dr. Gerlinde Teuber

Prof. Dr. Stefan Zeuzem

Med. Klinik II: Hämatologie / Onkologie, Rheumatologie, Infektiologie, Therapie der HIV - Erkrankung

Prof. Dr. Harald Burkhardt

Prof. Dr. Hubert Serve

Zentrum für Kinder- und Jugendmedizin

Klinik I: Stoffwechsel, Endokrinologie, Gastroenterologie, Ernährung, Pneumologie, Allergologie, Infektiologie, Neurologie und Neonatologie

Prof. Dr. Hansjosef Böhles

Prof. Dr. Stefan Zielen

Klinik für Pädiatrische Hämatologie, Onkologie und Hämostaseologie

Prof. Dr. Peter Bader

Prof. Dr. Thomas Klingebiel

Dr. Ulrike Köhl

Prof. Dr. Thomas Lehrnbecher

Prof. Dr. Dirk Schwabe

Zentrum der Neurologie und Neurochirurgie

Klinik für Neurologie

Prof. Georg Auburger

Prof. Rüdiger Hilker

Dr. H. Laufs

Dr. Matthias Lorenz

PD Dr. N. Müller

Prof. Dr. T. Neumann-Haefelin

Prof. Dr. Helmuth Steinmetz

Prof. Dr. Ulf Ziemann

Zentrum der Radiologie

Institut für Diagnostische und Interventionelle Radiologie

Prof. Dr. Thomas Vogl

Institut für Neuroradiologie

Prof. Dr. Friedhelm Zanella

Klinik für Nuklearmedizin

Prof. Dr. Frank Grünwald