Allgemeinchirurgie -
Dr. Christoph W. Strey

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Expertise

• Analyse der Zelldifferenzierung und Proteinsynthese primärer Hepatozyten in Kultur
  
• Proteom-Analyse des Zellstoffwechsels humaner Hepatozyten und Tumorzell-Linien
  
• Inflammatorische Regulation der Leberregeneration
  
  

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Methoden und Geräte

• Durchflußzytometrie, zweidimensionale Gel-Elektrophorese
  
• Protein-Analyse
  
• Quantitative-PCR, RT-PCR
  
• Entnahme und Zellkultur primärer Hepatozyten
  
• Zellbiologie, Kultivierung und Expansion
  
• Immunhistochemie
  
  

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Mitarbeiter

• Elsie Oppermann (Leitende Laborantin / MTA, Biochemie)
  
• Maria Rosa Marquez-Pinilla (Tumorbiologie, Multiplex Analyse)
  
• Maria Park (Laser capture microdissection)
  
• Sybille Beierlein (Zellkulturen, Protein Analyse)
  
• Kay Weipert (Histopathologie/Immunhistochemie)
  
• Lea Schamell (Zellkultur, Protein-Analyse)
  
  

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Publikationen

• Moench C, Burck I, Bug R, Bak YJ, Richter B, Schroeder R, Klarner A, Strey CW, Vogl T, Bechstein W. Hepatic Angiomyolipoma – a Rare Liver Tumor. Z Gastroenterol (2008) 46: 54-57.
  
• Wiegratz I, Kissler S, Engels K, Strey C, Kaufmann M. Umbilical endometriosis in pregnancy without previous surgery. Fertil Steril (2007) Sep 28.
  
• Strey CW, Winters M, Markiewski M, Lambris J.D. Partial hepatectomy induced liver proteome changes in mice. Proteomics (2005) 5: 318-325
  
• Strey CW, Spellman D, Stieber A, Gonatas JO, Wang X, Lambris JD, Gonatas NK. Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of hsp25, hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis. Am.J.Pathol (2004) 165: 1701-1718.
  
• Markiewski MM, Mastellos D, Tudoran R, DeAngelis RA, Strey CW, Franchini S, Wetsel RA, Erdei A, Lambirs JD. C3a and C3b Activation Products of the Third Component of Complement (C3) Are Critical for Normal Liver Recovery after Toxic Injury. J. Immunol (2004) 173: 747-754.
  
• Grotz W, Siebig S, Olschewski M, Strey CW, Peter K. Low-dose aspirin therapy is associated with improved allograft function and prolonged allograft survival after kidney transplantation. Transplantation (2004) 77: 1848-1853.
  
• Strey CW, Markiewski M, Mastellos D, Tudoran R, Greenbaum L, Lambirs JD. The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration. J. Exp. Med (2003) 198: 913-923.
  
• Manz T, Ochs A, Bisse E, Strey C, Grotz W. Liver support – a task for nephrologists? Extracorporeal treatment of a patient with fulminant Wilson crisis. Blood Purif (2003) 21: 232-6.
  
• Riedemann NC, Guo RF, Neff TA, Laudes IJ, Leller KA, Sarma VJ, Markiewski MM, Mastellos D, Strey CW, Pierson CL, Lambirs JD, Zetoune FS, Ward PA. Increased C5a receptor expression in sepsis. Journal of Clinical Investigation (2002) 110: 101-8.